Biology 1201A Lecture Notes - Lecture 7: Chondrocyte, Neuron, Centromere

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Once they"re made in the cell they stay put (microtubules & microfilaments are dynamic: microfilaments have a diameter of ~7 nm, involved in the gross movement of the cell. Note that this gross movement comes from within the cell (as opposed to cilia & flagella, which help move the cell from the outside): microfilaments are found in the cytoplasm, they"re composed of a protein called actin. Many molecules of actin join together to form an actin polymer; many actin polymers twist around each other to form actin filaments. Microfilaments details: recall, microfilaments are mainly involved in the gross movement of the cell. Microtubules details: these tubules are found in cilia & flagella, and also provide pathways for secretory vesicles to move through the cell. Microtubules are very important in cell division; they help form the mitotic spindle: one end of the microtubule is anchored to the microtubule organizing center (mtoc). This is what moves the flagellum or cilium.

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