Biology 1201A Lecture Notes - Lecture 26: Distal Convoluted Tubule, Stroke Volume, Peritubular Capillaries
2 Oct 2016
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When na+ enters the capillaries, water follows: tl:dr aldosterone works on the principal cell and causes blood to lose k+ and gain. Na+ (and thus gain water) this leads to increased stroke volume and thus increased blood pressure. What happens: in the -intercalated cell"s basolateral side, there is a channel that allows hco3- to travel from the cell into the capillary and simultaneously brings a cl- into the cell. 4 main transporters: on the apical side, there"s an active transporter (requires atp) that will send the h+ from the. Intercalated cell into the urine, and it can just be peed out. Aldosterone makes this transporter work super well: a second transporter on the apical side can send out h+ without using energy; instead it uses the na+ concentration gradient. Aldosterone also makes this transporter work super well: recall that cells have a lot of k+, but not a lot of na+. (most of the na+ is in the blood. )
