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Lecture 14

Biology 1201A Lecture Notes - Lecture 14: Alanine, Prokaryotic Small Ribosomal Subunit, Pepsin

Course Code
BIOL 1201A
Jennifer Waugh

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February 25, 2015
Translation – mRNA to protein
Prokaryote Versus Eukaryote
Simultaneous transcription and translation in prokaryotes
Simultaneous transcription and translation in prokaryotes
Ribosomes are the site of peptide synthesis

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tRNA structure
Secondary structure (red dots = modied bases)
Wobble in 3rd position of codon
61 codons specify an AA although there are not 61 dierent tRNA
Pairing between 1st two bases of codons always precise
“Wobble” in pairing at 3rd base in codon
Looser monitoring at this position by ribosome
Aminoacyl- tRNA synthetase
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