Biology 1202B Lecture 3: LECTURE 3
15 Oct 2018
School
Department
Course
Professor
Document Summary
Large molecules need something to move through a membrane. These molecules are moved by exo and endocytosis. Exo: getting rid of things: removing debris; things cell doesn"t want or need, also secreting things; hormones, signalling between cells. Bringing things into the cell that are quite large. The pinching off of the plasma membrane. Vesicle can move from the membrane into the cell. Table summarizes everything talked about so far. *in a normal membrane situation, water is always able to move across the membrane* Receptor mediated: very specific; specific signal extracellular signal intracellular response. Ligand binds outside of the cell; transmembrane proteins. Transmembrane integral protein needed for extracellular binding domain. Signal that must be transduced to get response. Involve phosphorylation carried out by kinases: phosphorylation activates or inactivates certain kinds of proteins. Signals are entirely exclusive to the receptor and signalling cascade mechanism. One protein phosphorylates the next, then the next, etc. Phosphatase enzymes remove phosphate groups from molecules: always active.
