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Health Sciences 2300A/B Lecture Notes - Integumentary System, Adipose Tissue, Dermis

Health Sciences
Course Code
HS 2300A/B
Jamie Melling

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Integumentary system- large organ that covers the body
Two components of skin epidermis (above) and dermis
Hypodermis is NOT part of the skin - fat and areolar tissue
Made up of almost entirely epithelial cells, organ must contain multiple tissues
Portion of skin made up of one epithelial tissue -stratified squamous
Keratinized squamous epithelium , keratin is a small protein that gives it integrity
and strength
Keratinocytes- carries melanin, pigment that gives colour to substance relates to
colour of skin
Melanocytes are cuboidal epithelial cells that actually produce melanin rapidly,
keratinocytes take-up melanin and spread it out
Melanin surrounds overtop of to protect
As tissues grows the deep keratinocytes are lost as well as tan
Langerhans cells-macrophages , may exists near the middle to clean up tissue
Stratum- "layer"
Active layer of epithelial , cells rapidly divide and pushed towards more superficial
layers as they die also known as "germ" layer- highly active and replicated
Spinosum is the largest in SIZE and made up almost entirely melanocytes all are
attached to each other
Granulosum- cells undergo cell death b/c they become too far removed from an
oxygen source that is only in the dermis. As they die they release lipid filled sacs,
hydrophobic creates a water proofing layer at granulosum
Lucidum only exists where there's thick skin - palms and feet , everywhere else layer
above granulosum is a corneum
Corneum- dehydrated and stuck together - many layers of dead cells
LEC 3: Integumentary System
2:08 PM
Lectures Page 1
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