Kinesiology 2230A/B Lecture Notes - Lecture 10: Myoglobin, Citric Acid Cycle, Catecholamine

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What is lactic acid- lactic? (1) under cellular conditions lactic acid loses and h+ and forms lactate: h+ associated with acidity (2) physiochemical principles (another explanation to (1)) If we add lactate (negative charge), h+ must increase: series of reactions dictate that h+ must increase. It"s not so much that we have hydrogen associated with lactic acid and it just gets cleaved off: scientists think its more about maintaining electrical neutrality --> ph goes down (more acidic) For the exam: increased lactate associated with increase in h+ (this is all we need to know; not going to ask about process (1) and (2) Once we"ve done this pyruvate can enter the kreb"s cycle (lactate is not a bad thing! Lactate in itself if good, we can break it down aerobically and get energy: we went from lactate to pyruvate to glucose- 6- phosphate, most of it is used as fuel.

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