Kinesiology 2236A/B Lecture Notes - Lecture 23: Cerebral Circulation, Heart Rate Variability, Middle Cerebral Artery
8 Apr 2017
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Concussion is displayed in a mixture of symptoms, nausea, confusion, dizziness, etc: headache, confusion, blurred vision, nausea, dizziness, lack of concentration. How long does it take to get better: typical symptom resolution in 7-10 days (70-80%, at 3-months, 20% still report symptoms, symptom profiles in adults mostly 7-10 days, in the other 20-30% Physiological changes in concussion: stretching/injury of axon, depolarization leads to increased neurotransmitter release. Glutamine the blue ball is released: neurotransmitter causes k+ to leave neuron and ca2+ to enter neuron. Glutamate is an excitatory neurotransmitter, causes k+ to leave the neuron/ca2+ to enter the neuron: na+/k+ tries to maintain homeostasis, using energy (atp) Increased glycolysis = increased lactate, cell cannot meet demand. Glycolysis will increase (anaerobic glycolysis will cause increase in lactate: metabolite buildup causes axonal swelling. Axonal swelling causes decreased functioning of the concussion: decreased function.
