BI110 Lecture Notes - Lecture 7: Osmosis, Cytosol, Hydrophile

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Passive transport of molecules across a membrane through aid of a transporter. Becomes saturated at high concentrations of transported substance. Depends on membrane proteins and is specific for certain substances: channel proteins. Form hydrophilic channels in the membrane through which water and ions can move. Most proteins that carry out facilitated diffusions of ions are controlled by gates that open or close their transport channels: aquaporin. Water molecules move through the channel by being handed off to a succession of hydrogen-bonding sites on the channel. Outside cell cytosol: k+ voltage-gated channel. With normal voltage, the activation gate is closed, and k+ cannot move across the membrane. In response to a voltage change, the activation gate opens, and. Cytoplasm outside cell: carrier proteins. Bind a specific single solute and transport it across the lipid bilayer (uniport transport) Undergo conformational changes that move the solute-binding site from one side of the membrane to the other.

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