PS268 Lecture Notes - Lecture 7: Macular Degeneration, Cefazolin, Fentanyl

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There are numerous routes of administration for drugs and the setting as well as the desired result have an impact on deciding which route is the preferred choice. This makes the drug"s effects susceptible to being diluted or negated by digestive enzymes, food in the stomach or metabolizing in the liver (hart et al. , 2016). Even with this risk people continue choose non-invasive oral administration in great numbers for legal drugs such as acetaminophen at home and in clinical settings as well as illegal drugs such as mdma. Parenteral drug administration is also very common, particularly intravenously because it is being injected directly into the bloodstream it creates the (cid:373)ost rapid o(cid:374)set of the drug"s effects (hart et al. , 2016). Intravenous injections also allow for highly concentrated doses because the blood vessel walls are insensitive, leading to a high risk of overdose and death from illegal drugs such as heroin and crack cocaine.

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