BIOL 2020 Lecture Notes - Lecture 3: Cell Adhesion, Intermediate Filament, Integrin
28 Sep 2017
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Document Summary
Cell-cell adhesions: cell adhesion molecules (cams): proteins located on cell surface involved in binding with other cells. Helps cells stick to each other & to surroundings: extracellular matrix (ecm, specialized cell junctions, cell adhesion molecules, cadherins: type of transmembrane proteins. Play important role in cell adhesion forming adheren junctions to bind cells within tissues together: cams. Collagen: most abundant proteins in bodies, found in muscles, bones skin, blood vessels, gives strength to skin & elasticity, main structural protein. Fibronectin: glycoproteins that binds to membrane-spanning receptor proteins called integrins, specialized cell junctions. Joins intermediate filaments of one cell to those in a neighbor. Gap junctions (communicating junctions: allow for direct chemical communication b/t adjacent cellular cytoplasm through diffusion, cylinder for transportation is called connexon. Connexon complex stretches across cell membrane to interact with adjacent cells connexon: allows efficient communication without escape of molecules or ions into.
