BIOL 4380 Lecture Notes - Lecture 5: Dorsal Root Ganglion, Afferent Nerve Fiber, Pseudounipolar Neuron
17 Feb 2018
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The processes extend all the way to the skin, muscles and joints. Pseudounipolar neuron has just one process and branches out into 2 long branches that move away from the cell body. Dorsal root ganglia are a part of the. As the stimulus, for example stretches, the membrane of neuron channels open, depolarization happens and aps are initiated. Afferent fibers where there"s no encapsulation free nerve endings: receptor potentials, the strength of stimulus determines whether the ap is generated. It can be below threshold, so ap won"t be generated: one recently identified family of receptors that sense stretch of membrane are large. There are 2 of them, piezo 1 and 2, 2 appears to be the more prominent in the mechanosensory neurons. Piezo proteins have a very large transmembrane domains, up to 34. Do this on forearms, and hands, you will notice that it takes a wider distance to start feeling 2 distinct points.
