KINE 2031 Lecture Notes - Lecture 4: Renal Blood Flow, Extracellular Fluid, Exercise Intensity
2 Jul 2018
School
Department
Course
Professor
Tubular Component of Nephron
-Formed of epithelial cells
-Bowman’s Capsule proximal Loop of Henle Distal Collecting Ducts
-Bowman’s Capsule: double walled & collects fluid filtered from glomerular capillaries
-Proximal in cortex, loop of Henle extends to medulla
-Juxtaglomerular apparatus: important in regulating kidney function. Both vascular &
tubular
oascending limb of tubular forks through afferent & efferent arterioles
Cortical & Juxtamedullary Nephrons
1. Juxtamedullary Nephrons
-Have loop of Henle that extends deep into medullary
-Vascular component of peritubular capillaries in loop of Henle called vasa recta
-Long looped nephron important in establishing medullary vertical osmotic gradient
-Performs concentration of urine
-Vasa recta & loop of Henle important in creating urine at different concentrations
depending on needs of body
2. Cortical nephrons
-Loop of Henle dips slightly into medulla
-Perform excretory & regulatory functions
Three Basic Renal Processes
1. Glomerular Filtration: no discriminant filtration of protein free from glomerulus into BC
-NO blood cells or proteins gets filtered.
-All other constituents in blood – H20, nutrients, electrolytes, wastes get filtered
2. Tubular Reabsorption: selective movement of filtered substances from tubular lumen
peritubular capillaries
-Substance of value are selectively returned to blood. This material is retained in body
for circulation
-Material left is passed to pelvis where its eliminated
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Bowman"s capsule proximal loop of henle distal collecting ducts. Bowman"s capsule: double walled & collects fluid filtered from glomerular capillaries. Proximal in cortex, loop of henle extends to medulla. Both vascular & tubular: ascending limb of tubular forks through afferent & efferent arterioles. Have loop of henle that extends deep into medullary. Vascular component of peritubular capillaries in loop of henle called vasa recta. Long looped nephron important in establishing medullary vertical osmotic gradient. Vasa recta & loop of henle important in creating urine at different concentrations depending on needs of body: cortical nephrons. Three basic renal processes: glomerular filtration: no discriminant filtration of protein free from glomerulus into bc. No blood cells or proteins gets filtered. All other constituents in blood h20, nutrients, electrolytes, wastes get filtered: tubular reabsorption: selective movement of filtered substances from tubular lumen peritubular capillaries. Substance of value are selectively returned to blood. This material is retained in body for circulation.
