HUBS192 Lecture Notes - Lecture 41: Ascending Limb Of Loop Of Henle, Carbonic Anhydrase, Collecting Duct System
Document Summary
But cell ph a bit lower (closer to 7): because metabolism in cells produces acid. Concentration of h+ regulated/controlled by buffering and excretion ph regulation: Acid load comes from 2 diff. sources: we oxidise glucose to get atp that was light energy captured by the plants, we produce co2 (big acid load) This is why we need to keep breathing to get rid of co2, thus overall the acidic load from co2 is taken care of by. Hb buffering to transit to the lungs, and also keep breathing to exhale co2: non-volatileacids: H+ needs to be buffered first by bicarbonate (taken care of) and then excreted (done by splitting the acid up into. H+ and its anion; anion is excreted at the kidneys and h+ is taken care of by the bicarbonate system); whole body buffering; bone phosphoric acid helping as well;