BIOL 430 Lecture Notes - Lecture 14: Inhibitory Postsynaptic Potential, Neuroglia, Barbiturate
Document Summary
Either excitatory or inhibitory: hyperpolarize it so it becomes less likely to produce an action potential. Some neurotransmitters make the membrane potential more negative . Question: depolarize means to make the cell (usually at -70 mv) more or. De-polarize: makes cell less negative (more positive) want to go from -70mv to - Ex. neuron fires caused local potential, need graded potential that is enough to. 55 mv*** > +30 mv > -70 mv. Less negative?? cause enough de-polarization to set off action potential. For example: gaba is the main inhibitory nt and opens cl channels. Barbiturates: do not allow post synaptic signal to be excitatory > they facilitate gaba binding to its receptor site** inc. inhibitory response. Thousands of axon terminals synapse on the dendrites or cell body, delivering signals from other neurons. Modulation of synaptic activity is key to neural communication.
