BIOL 430 Lecture Notes - Lecture 29: Tetany, Hypocalcaemia, Myocyte

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2 Oct 2020
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Higher frequency stimuli (eg. , 20 stimuli/s) produce temporal (wave) Each new twitch rides on the previous one generating higher tension. Only partial relaxation between stimuli resulting in fluttering, incomplete tetanus contraction called complete (fused) tetanus. Unnaturally high stimulus frequencies (in lab experiments) cause a steady, Single muscle fiber (only in a lab) Electrical stimulus for a single muscle fiber (second graph) > upward slope. Not enough time within each contraction for ca to be pumped back incomplete tetanus. Where we operate! third graph- max out tension derived from a single muscle cell. No matter how many stimuli maxed out. Each muscle fiber generated the same amount of tension based on stimulus. A condition that is due usually to low blood calcium (hypocalcemia) and is characterized by spasms of the hands and feet, cramps, spasm of the larynx, and overactive neurological reflexes. Tetany is generally considered to result from very low calcium levels in the blood.

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