KIN 494 Lecture Notes - Lecture 4: Nebulin, Skeletal Muscle, Troponin

46 views4 pages
Published on 3 Sep 2015
September 1, 2015
KIN 494 – Module 2 notes
1. Importance of muscle cell components
a. Nucleus
i. DNA - Contains all the information that tells cells what to do
b. Mitochondria
i. Krebs cycle
ii. Production of energy for the muscle (ATP)
2. Only 20-25% of energy converted to mechanical work
3. Structure of a Single Muscle Fiber
a. Sarcomere
i. Functional unit of skeletal muscle***
ii. Where all of the contraction occurs
iii. The space from one Z disk to another
iv. Very organized structure with striations
v. Thin Filaments: Actin, Troponin, Tropomyosin
vi. Thick Filaments: Myosin
vii. Titin, nebulum, etc
viii. Under microscope
1. Light band – I band (either side of Z disk)
2. Dark band – A band (myosin, thick filaments of sarcomere)
ix. When muscle contracts
1. I band gets smaller (shrinks because Z disks get pulled closer
to each other)
2. A band – length stays the same (Thick filament doesn’t change
length, just pulls thin ones close to the,)
x. Not just actin and myosin. Whole bunch of other proteins in a fluid
xi. Titin and Nebulin are anchor proteins that hold the myosin and actin
respectively in place
b. Thick Filament – Myosin
i. Each thick filament holds about 200+ myosin molecules
Unlock document

This preview shows page 1 of the document.
Unlock all 4 pages and 3 million more documents.

Already have an account? Log in

Get OneClass Notes+

Unlimited access to class notes and textbook notes.

YearlyBest Value
75% OFF
$8 USD/m
$30 USD/m
You will be charged $96 USD upfront and auto renewed at the end of each cycle. You may cancel anytime under Payment Settings. For more information, see our Terms and Privacy.
Payments are encrypted using 256-bit SSL. Powered by Stripe.