BIO 3422 Lecture Notes - Lecture 1: Hormone Response Element, Extracellular Fluid, Secretion
Document Summary
Tissues and organ systems function to maintain. I(cid:374)di(cid:448)idual (cid:272)ells a(cid:374)d (cid:396)epeats o(cid:374) a(cid:374)d o(cid:374). Therefore, cells must be able to communicate (cid:448)ia : directly. Secretory cell = (cid:396)eleases (cid:373)esse(cid:374)ge(cid:396) that (cid:271)i(cid:374)ds to . Receptor on target cell = receive messenger. Diffuse through interstitial fluid to target tissue. Channel linked receptor: transmembrane protein with a specific receptor for hydrophilic messenger that causes channel to open or close which allows ions to move through membrane, fast channel. These extra cellular messengers bind to g-linked membrane bound receptor. These eventually bring about a biological response of the target cell. Second messengers that activate a protein kinase to bring about a response camp: cgmp, dag. Second messenger that binds to smooth er (holds onto calcium) to open calcium channels to exit, where it will bind to calmodulin which activate a protein kinase to bring about a response.
