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Department
Biology
Course
BIOL 3150
Professor
Cam
Semester
Fall

Description
Chapter 12 • Because prokaryotes lack nuclei, transcription and translation can occur simultaneously  Allows for attenuation to control transcription of Trp operon and terminate transcription at operon  Formation of shorter loop stimulates Rho-independent termination of transcription  Stalled RNApolymerase by hairpin allows Rho helicase enzyme to terminate transcription – Rho breaks RNA-DNAbase paires o Many genetic elements contribute to transcription of eukaryotic gnnes o Three distinct RNApoly in eukaryotes  RNApoly I = rRNA(ribosomes)  RNApoly II = protein coding genes  RNApoly III = tRNA • RNApolymerase has low affinity for DNA, so recruited by DNA-binding protein o Different sequence motifs for promoter of each RNApoly, RNApoly II = TATAbox o Eukaryotic PIC consists of many protein subunits including those associated with RNApolymerase, general transcription factors (GTFs) and coactivators • Phosphorylation of serine of carboxyl Terminus promote movement from initiation to elongation • Eukaryotic promoters often contain a multitude of regulatory modules bound by various classes of transcriptio
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