BIOL3190 Lecture Notes - Lecture 29: Lysine, Bioinformatics, Comparative Genomics
Document Summary
Can figure out what is there between the different gut microbiomes. Beta globin gene that codes for 2 genes in hemoglobin. Beta globin gene cluster differ a little bit from each other. Globin gene that duplicated into alpha and beta. Beta globin gene duplicated that became adult and fetal beta globin. At some point, there was a whole genome amplification event so that cell had 2 copies of that gene. Comparative genomics is how you identify what is uniquely human. Figuri(cid:374)g out (cid:449)hat"s (cid:449)hat (cid:271)(cid:455) gazi(cid:374)g at ta(cid:271)les. Functional genomics how we use information to figure out function of genes. Genes transcribed in muscle cells are important for muscle function. Only way to do microarrays is to compare 2 samples. Comparing for each spot which represents a sequence. Can hybridize with one but not the other. Took a bunch of expression data between a bunch of patients and use a computer to identify patterns in data.
