BIOLOGY 1A Lecture Notes - Lecture 4: Plant Cell, Intermediate Filament, Microfilament
22 Jan 2018
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*17 points of lc available, 12 max: cytoskeleton, extracellular matrix. Intercellular connections: cytoskeleton: network of fibers that organizes cell activities/structures. Organizes the cell"s structures and activities, anchoring organelles: microtubules (cid:498)big(cid:499, microfilaments (actin filaments) (cid:498)small(cid:499, intermediate filaments (cid:498)medium(cid:499) Has 3 molecular structures: roles of the cytoskeleton: support, motility, and regulation. Vesicles inside the cell travel along (cid:498)monorails(cid:499) provided by cytoskeleton: microtubules: 25 nm: tubulin protein: a dimer aka 2 separate polypeptides, microfilaments: 7 nm, intermediate filaments: 8-12 nm. Cytoskeleton has fibers/filaments that run across the cell, there are proteins that literally walk across these structures and carry vesicles. Binds atp, hydrolyzes to adp, moves a leg mechanical motion fo the protein: components of the cytoskeleton, microtubules, centrosomes and centrioles. Microtubules control beating of cilia and flagella aka locomotor appendages of some cells. Dynein: motor protein that drives the bending movements of cilium or flagellum: microfilaments. Function in cellular motility, contain the protein myosin in addition to actin.
