NUSCTX 10 Lecture Notes - Lecture 16: Retinol, Beta-Carotene, Chylomicron
29 Mar 2016
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Storage in cells with fat toxicity greater (can accumulate over time) Absorption (1) fsv + fat + bile acid micelles (2) m absorbed by enterocytes in si chylomicrons (3) c (amount of fat entering impacts chylomicron packaging) circulate thru lymph blood. Liver (versus wsv goes straight to the liver), beneficial because tissues get fsv needed before fsv is stored in liver (4) stored in fat or attached to transport protein. 3 active forms (rectinoids) (1) retinol (2) rectinal (3) retinoic acid. Va orecursor: beta-carotene (sources: fruits and vegetables)- on its own acts as an antioxidant with double bonds. Body retinol, retinal and retinyl ester (stored in liver) can be converted) Body retinal can be converted into acid but not vice versa. Vision: retinoic acid: maintains cornea, retinal: conversion to light energy into nerve impulses in rod cells of the retina form image in the dark, night vision.
