PSYCH 110 Lecture Notes - Lecture 7: Nmda Receptor, Ligand-Gated Ion Channel, Magnesium
Document Summary
If you touch the siphon, the slug pulls in it"s gils to protect. But if you keep touching the siphon and nothing bad happens, the slug will habituate. Short term habituation is within a couple of minutes - stop doing it and touch siphon again in an hour it will forget about it and contract gils. Long term habituation is a couple of days. Different mechanisms for short and long term. Sensory axon decreases number of synapses onto motor neuron - responsible for long- term habituation. Smaller epsp, less likely to fire action potential. Long-term because structural change - to grow back axon terminals. Glutamate receptors are chemically modified so they are less responsive to glutamate - responsible for short-term habituation. Fewer vesicles are released from the sensory neuron - responsible for short-term. Decrease the amount of glutamate, decrease epsp, won"t get to threshold, less likely to fire action potential. Hebb"s hypothesis: neurons that fire together, wire together .
