BIOL 118 Lecture Notes - Lecture 2: Signal Recognition Particle, Nuclear Pore, Golgi Apparatus
18 Feb 2017
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Document Summary
Nucleases- digest rna/dna: endocytosis, pinching off of the plasma membrane resulting in the uptake of material from outside of the cell, there are 2 types of endocytosis. Studded with ribosomes for protein synthesis is continuous with the nuclear envelope. A 20 amino acid sequence that directs proteins to the rer. It is removed from protein: rna binds to the ribosome in the cytosol, ribosome synthesizes the er signal sequence. The er signal sequence binds to a signal recognition particle (srp) The signal recognition receptor then binds to the srp receptor in the er membrane. Protein synthesis continues pushing the new protein into the rer and passes through the translocon ( a pore that the new protein gets pushed out of) Sort the proteins to put together those going to the same place. Nuclear localization signal allows a protein to enter the nuclear pore complex. Er signal sequence signals a protein to be made in the rer.
