CAS BI 216 Lecture Notes - Lecture 7: Chromosome Segregation, Enterobacteria Phage T4, Arginine
19 May 2017
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Linkage: genes mapped in small units - overlapping maps -> greater. Can never see beyond 50 mu (only 50% recombination: possible meiosis events. Dco - 0% recombinants (look like parents. Dco 3 strans - two different strands recombine with one (both sets of 2 can do this to the 3rd) - 50% recombinance. Dco 4- strand - 100% triple crossovers -> get to 50 : genetic maps can understimate physical distance between genes. Reverse mutation - less common; mutant allele -> wt. Depends on size (larger genes -> more mutations) 7. 3 - what mutations tell us about gene structure. Unlinked and same mutant phenotype (aa bb = aa bb: example of complementary genes - hearing in aabb. Dominant mutant allele - will not complement if they are recessive and unlinked - compliment if they are in the same gene - fail to compliment. Mutations may be on different places of the gene, but still same gene.
