CAS AN 102 Lecture Notes - Lecture 3: Maurice Wilkins, Mendelian Inheritance, Allele Frequency

• School: Boston University
• Department: Anthropology
• Course: CAS AN 102
• Professor: James Schmidt

Document Summary

Blending inheritance: each parent contributes to the offspring, contributions halved at each successive generation, issue w/ natural selection: advantageous traits are diluted w/ each new generation. Tay-sachs: i(cid:374) (cid:272)o(cid:374)trast to polyge(cid:374)i(cid:272) traits phe(cid:374)otypi(cid:272) traits that result fro(cid:373) the (cid:272)o(cid:373)(cid:271)i(cid:374)ed action of more than one gene (most complex traits are polygenic) Evolution: modern definition change in allele/gene frequencies over time in a population: allele frequency measure of the relative frequency of an allele at a particular genetic locus in a pop, pop. Community of individuals w/in a species where mates are usually found. Genome complete dna sequence of a set of chromosomes: (cid:862)ge(cid:374)e(cid:863) & (cid:862)(cid:272)hro(cid:373)oso(cid:373)e(cid:863, 3,000,000,000 base pairs, 25,000 genes. Karyotype: 46 human chromosomes, 23 pairs (one set from each parent) Each strand serves as a template for a new strand. While separated, unattached nucleotides attracted to free ends of each strand. Missense mutation causes different amino acid to be appended to protein.