CAS BI 203 Lecture Notes - Lecture 3: Phosphatidylethanolamine, Phosphatidylserine, Fluid Mosaic Model
18 Jan 2020
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Document Summary
Overall role selective barrier that regulates the internal composition of the cell. 1 fundmental structure phospholipid bilayer a impermeable to most water soluble molecules. Phosphatidyl ethanolamine c phosphatidylserine d sphingomyelin e phosphatidylinositol much lower quantity will leaflet inner leaflet leaflet leaflet inner outer outer keyroles in cellsignaling endocytosis other events talk about more later. Phospholipid structure is responsible for basic function of membranes separating aqueouscompartments. Bilayer interior consists of hydrophobic fatty acid chains solublemolecules lie ionsdamost biological molecules. Unsaturated fatty acids have one or more double bonds which makes kinks in chain whichkeeps them from packingtogether. Lipids and proteins are free to diffuse laterally within the membrane increases fluidity impermeable to water. 3 phospholipids are asymmetrically distributed between inner a outer leaflet sphingomyelin and phosphatidylcholine i additional membrane lipids in animal cells outer membrane. 1 glycolipids mostly outer leaflet with carbohydrateportions exposed on cell surface. Note plasma membrane not all proteinslarger than lipids lipid 05090protein 5090phospholipidscmolecules.
