CAS BI 315 Lecture Notes - Lecture 4: Hyperkalemia, Endocrine Disease, Aldosterone
Document Summary
Cas bi315 - lecture 4 transport within the cell and potentials. Tonicity: hyperosmotic , hypertonic, shrinks isosmotic, isotonic hyposmotic , hypotonic, water comes in. 300 mosm is the normal solute concentration if shrinks or swells the cell can break and die. Nerve cells generate electrical signals that allow them to signal each other cell with big k, small ca, small cl, big protein, and small na inside; big ca, big na, big. Sodium-potassium atp-ase, moves 3 sodiums out for every 2 potassiums in pumps set up gradients to serve physiological functions. 90 mv inside: small na inside and large na outside, 15 mm and 145 mm, ena+ = 61 log (145/15) = +60 mv: 130 mv out of equilibrium, but the sodium would eventually help the cell reach. Figure 6. 16 the bigger the stimulus the bigger the depolarization (see figure), this is called graded. Potential: action potential is not graded potential, one size of stimulus, depolarized, excited, hyperpolarized, inhibited.
