CGS NS 202 Lecture Notes - Lecture 3: G2 Phase, Dna Replication, Primase
17 Oct 2017
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Then goes to g2 where it checks that the duplicated dna is correct, chromosome diseases occur in g2 phase. If it is incorrect, mitosis does not happen. They used isotopes (different version of element that has a different # of protons or neutrons). Used nitrogen 14 isotope called heavy nitrogen with an extra proton 15. The whole study noted that the pattern could only be observed if the dna molecule has a parent strand: dna could be replicated conservative aa bb, semiconservative: where it gets half and half and then dispersive. Dna replication process (on quiz): separate two strands of parent dna by helicase at the replication fork. exposing free bases (adenine, guanine, ect) , unwind them by helicase, then binding proteins come. Primase comes and attracts a rna primer that gives us starting materials to make a new strand, it is also important because dna polymerase only works with primer. Dna polymerase: replaces primase and binds free bases.
