CAS PS 211 Lecture Notes - Lecture 26: Fetus, Antiserum, Epitope
15 Sep 2016
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Document Summary
Serology- study of reactions between antibodies and antigens. Naturally acquired active immunity- antigens enter body naturally, body produces antibodies and specialized lymphocytes (ex when person get diseases can be lifelong or confer) Naturally acquired passive immunity- passes from mother to fetus via placenta or from mother"s milk. Artificially acquired passive immunity- intro of antibodies from animal or person who is already immune, antibodies found in serum- antiserum, blood fraction rich in antibodies called gamma globulin,antibodies-immunoglobulins. Antibodies recognize and interact with specific regions on antigens- antigenic determinants (epitopes), nature depends on size, shape, and chemical nature/structure. Haptens- low molecular weight, not antigenic unless attached to carrier, hapten will react with antibody independent of carrier molecule ex: penicillin- not antigenic but initiates immune response when combined w/ serum protein. Nature of antibodies- proteins made in response to antigen, can recognize and bind to antigen, help neutralize or destroy antigen, highly specific in recognizing antigen that stimulated orig. formation.
