CAS PS 241 Lecture Notes - Lecture 4: Familial Hypercholesterolemia, Frontal Lobe, Epigenetics
10 Jan 2017
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Processes of brain development (3 steps, all mostly prenatal: 1. Neurogensis o creation of new neurons, proliferation of neurons through cell division (weeks. 4-18) o 250k new neurons per minute o at 18 weeks, neurogenesis complete (mostly: 2. Chimps have 12 month gestation (humans have nine months) At birth: chimp brains are 50% of adult size. Human brains are 50% of adult size at 3 months. It seemed we were forced out of the womb early. Neural differentiation, including the lobes o synaptic density (this is both synaptogensis and pruning between birth and two years) less dense at birth: 4. Neuronal maturation o begins 15th prenatal week, but continues up to age 2 o axons thicken and elongate, o arborization. Branching of the dendrites where the dendrites begin to connect with one another o 5. Synaptogenesis and 6. synaptic pruning = synaptic density.
