CAS PS 333 Lecture Notes - Lecture 1: Major Depressive Disorder, Bipolar Disorder, Health System

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Two things that you need to consider when talking about drugs in humans: side effects + therapeutic effects: antadonia: loss of interest in life (feeling empty, unipolar depression: anti-depressants, suicide ideation: ideas about suicide. Idea that she is not suicidal: mood disorder, ssri. Bipolar depression: gets anti-depressants but also get mood stabilizers [they are a therapeutic indication: two subclasses of symptoms, depressed symptoms, mania [mood-stabilizer treatment] Changes in sleep: ge(cid:374)es: they do(cid:374)"t cause the diseases, pre-disposed, combination of all of the genes and other genetic mechanisms that is written in your dna + rna as an interaction with everything else that you do. In women will be diagnosed with depression: estrogen + progesterone. 1/8 in men will be diagnosed with depression: health care system is one of the most important financial crisis of our age. We spend more than we take in and it is affecting our economy.

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