NPSY 22b Lecture Notes - Lecture 14: Optogenetics, Safe House, Dentate Gyrus
6 Sep 2016
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Document Summary
Cognitive decline and memory impairment that affect daily functioning. Change in sense of humour a sign of impending dementia" in the news. Recent suggestion in the news that robin williams had lew body dementia. Parkinson"s-like movement disorders (rigid muscles, slow movements, tremors Destruction of medial temporal lobe area related to chronic, sever alcoholism (~ 25 years) Confusion, disorientation, sleepiness, ataxia (strange gait), under-nutriotion, hypothermia. Might see them wearing coats in summer. Famous patient p. z. - professor emmeritus and famous scientist. Thiamine deficiency because alcohol makes it more difficult for the body to absorb it. Thiamine: helps cells produce energy from carbohydrates. Hippo, medial temporal lobes, amygdala, frontal lobe. Riding bike, playing piano (tracing like with h. m. ) Sever gross atrophy (brain shriveling up) plaques and tangles, dimentia. Round aggregates of insoluble cellular trash consisting of beta-amayloid protein. Affinity for regions where the majority of synaples lie. Twisted fibers of tau protein that biold up in cytoplasm of cell bodies.
