BIOL 1100 Lecture Notes - Lecture 2: Cyclic Adenosine Monophosphate, Cyclic Nucleotide, Ion

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6 Feb 2017
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Action Potentials
Local potentials
o Injection of K+ changes the voltage the most because there is already so much inside, many
channels open
Even at the injection site, the voltage doesn't stay up, it fades away because some
ions have flowed out of the cell
Over time (V1-->V3), losing net voltage
o This is what happens when you don't set it up for action potentials
Need to set it up to be able to recharge
"All-or-none" action potentials
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o K+ ions find V-gated Na+ channels --> more Na+ comes in --> + charge activates next V-
gated Na+ channel, etc.
o At the initiation site, might look a little different
If there is a synapse at initiation site, there is a depolarization hump before the voltage
reaches depolarization threshold
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