BIO 263 Lecture Notes - Lecture 9: Population Bottleneck, Null Hypothesis, Genotype Frequency

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If all the requirements are met for a hardy weinberg model would be considered a null- hypothesis. Nothing is changing and there is no effect. Hardy-weinberg principle could be considered a null-hypothesis. Two alleles possible in this case m and n. Calculate observed allele frequencies from the blood samples. Use observed genotype frequencies to calculate expected genotype frequencies. Mn blood time when compared to different populations shows that evolution is not occurring because the observed is similar to the expected. Hla is the most diverse set of loci in human and the most that we will talk about. All alleles in this case show codominance. All the alleles are expressed in the phenotype. Normally it would only express 1 of the set of alleles. More likely to reproduce due to evolutionary fitness. In case study they observed the genotype of 125 havasupai native americans to test their hla genes. Why are hla genes not in equilibrium.

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