BIO 263 Lecture Notes - Lecture 10: Allele Frequency, Weak Interaction, Antimicrobial Resistance
Document Summary
Natural selection is different from gene flow. Also if other alleles aren t acting in opposition. Is a weak force for sexually reproducing species. Example is bacteria where they go through many generations in short period of time. Leads to mutation being the biggest evolution force in these species. Example of this is antibiotic resistance being built up in bacteria that is now becoming a bigger and bigger issue for us than before. Vast majority of mutations causes a decrease in fitness and therefor never changes. Beneficial mutation occurs rarely but when it does it then spreads via selection because it is better. Significant in microbes due to their short generation times. New alleles into every individual after every generation. In eukaryotes mutations rarely cause departure from hardy-weinberg expectations. Just may not code for something that affects fitness. Each of us has approx 1. 1 new alleles created by mutation when compared to our parents.
