FSN 210 Lecture Notes - Lecture 16: Hepcidin, Ferroportin, Ferritin
Document Summary
Hemoglobin delivers oxygen to body cells and carries away carbon dioxide. Mucosal cells in the intestines store excess iron. Releases iron to a transport protein which gives the iron to the blood. Storage- ferritin binds and stores iron to prevent it from entering the bloodstream. Ferritin- storage form of iron in mucosal tissue. Ferroportin- the door to circulation that allowed ferritin through. Hepcidin- prevents from having too much iron in the body by promoting degradation of ferroportin. Women vegetarian 33 mg/day men vegetarian 14 mg/day. Zinc is needed for enzyme and immune functions, also hormone and activity. Cytochrome c oxidase catalyzes last step of electron transport chain. Seafood, nuts and seeds, whole grains and cereals, chocolate. Essential component of thyroid hormones essential component of metabolism. Can get a goiter from toxicity and de ciency. Stored in liver, pancreas, muscle, kidneys and thyroid. Excess leases to impairment of sulfur and protein and metabolism.