Permachart - Marketing Reference Guide: Anterior Grey Column, Myasthenia Gravis, Bethanechol
Document Summary
Alzheimer"s disease: the loss of cholinergic neurons at the basal nucleus of meynert. Lambert-eaton syndrome: the loss or dysfunction of acetylcholine release at the neuromuscular junction. Clostridium botulinum toxin: a neurotoxin which causes paralysis by decreasing ach release from the axon terminal. Clostridium tetanus toxin: a retrograde block at the peripheral anterior horn cells the protein blocks the inhibitory transmission (i. e. , it prevents glycine release), causing tetanospasm. Direct cholinomimetic: a carbachol which mimics ach at all receptors (muscarinic and nicotinic) Tetrodotoxin: prevents the conduction of action potentials by blocking na+ channels. Cholinergic neurons: cerebral cortex, anterior horn of the spinal cord, pre-ganglionic neurons (sympathetic and parasympathetic, special sympathetic post-ganglionic neurons, such as the eccrine (sweat glands), blood vessels of the penis and clitoris, and blood vessels of the face. Parasympathetic neurons: cranio-sacral, cranial nerves 3, 7, 9, 10, sacral segments 2, 3, 4.
