ANSC 340 Lecture Notes - Lecture 11: Sertoli Cell, Endometrium, Cyclic Adenosine Monophosphate
4 Oct 2016
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Document Summary
Hormone receptors- role in whether or not a hormone is capable of causing a response. The reason gnrh stimulates release of lh/fsh (receptor in anterior pituitary) but not ot. There are times during the estrous cycle when the hormone is present in the blood but there"s no response because receptors are not yet present on cells (hanging out, eventually degraded) Stimulates estrogen production (from testosterone)- activates aromatase (female and male) Stimulates spermatogenesis in male (binds to sertoli cells) Stimulates lh-r formation on granulosa cells of graafian follicles to prepare for ovulation (female) Granulosa/theca interna always refers to female; lh receptors in follicle; thus lh can cause ovulation. Ovulation- by binding lh-r on granulosa cell. P4 production by cl (binds luteal cells theca interna and granulosa cells become luteal cells) Binds lh-r on theca interna cells to stimulate testosterone production which crosses basement membrane to granulosa cell, where it is converted to estrogen.
