PSYC 323 Lecture Notes - Lecture 8: Axon Terminal, Monoamine Oxidase A, Brain-Derived Neurotrophic Factor
31 Oct 2016
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Both a and b (nature and nurture) Temperament (it"s biological) = typical patterning of response to one"s environment. Rejects change (not gonna do something different) Warms up to change (shy at first but ends up being your bff) Maternally deprived rats found they were hyperreactive to anxiety-provoking events in adulthood (were more likely to access that enviorn event as a threatening situation) Took rat pups (12-20 days old) separated from mom for 8-24 hrs. Increased corticosterone responses acute activation of the locus ceruleus. One of the aminergic nuclei releases norepinephrine. Both a and c (depression and ptsd) Modulates serotonin system (modifications of serotonin system tied to hyper-responsiveness of limbic-hpac axis) Higher rates of neuron and glial cell death. Especially in hippocampus leads to smaller hippocampal volume. Hippocampal volume primary site for negative feedback for regulating cortisol. Less shutdown of cortisol production in the evening greater total production of cortisol. Inhibit growth of new cells in the hippocampus.
