BMS 420 Lecture Notes - Vascular Smooth Muscle, Coronary Artery Disease, Angina Pectoris
Document Summary
Map baroreceptors discharge medullary cardiovascular centers map. If map - venous tone, cardiac contractility ( esv), arteriole tone. Bp = co x tpr (total peripheral resistance) Renin-angiotensin aldosterone system involved in long-term regulation of arterial blood pressure. Renin acts on angiotensin ai (angiotensin i) Ace (angiotensin converting enzymes) act on ai aii. Aii renal sodium and fluid retention blood volume cardiac output arterial pressure. Atrial natriuretic peptide regulates long-term arterial blood pressure. Atrial distension/sympathetic stimulation/angiotensin ii/endothelin heart anp. Anp svr (systemic venous return) arterial pressure. Anp cvp (cardiovascular pressure) co arterial blood pressure. Anp gfr natriuresis/diuresis blood volume cvp co arterial blood pressure. Anp gfr renin release angiotensin ii aldosterone. Both decreased angiotensin ii and decreased aldosterone lead to natriuresis/diuresis. Angiotensin ii/hyperosmolarity/decreased atrial receptor firing/sympathetic stimulation pituitary vasopressin. A tale of coronary artery disease and myocardial infarction: nabel and braunwald. Organs vary greatly in their resting blood flow and in the maximum blood flow which can be attained.
