Carbon monoxide, hypoxias

3 Pages
Unlock Document

Colorado State University
Biomedical Science
BMS 420
Charles Miller

9 November Carbon monoxide poisoning Odorless gas High affinity for hemoglobin Symptomless Carbon monoxide is particularly soluble at low partial pressure because of the huge affinity for hemoglobin. Oxygen solubility in general is higher at the lower partial pressures. (In normal individuals, the occupation of hemoglobin with carbon monoxide is about 1 – 2%; in smokers or individuals in large cities, the amount may be 10%). The high binding of carbon monoxide with Hg (carboxyhemoglobin) at low partial pressure (200 times higher affinity compared to oxygen) makes carbon monoxide poisoning all too common. Oxygen-hemoglobin dissociation curve Right shift with lower pH, higher temperature, greater PCO2, greater amount of 2,3-DPG Classifications of Hypoxias Hypoxic hypoxia Low arterial PO2 Typical causes: high altitude; alveolar hypoventilation; decreased lung diffusion capacity; abnormal ventilation-perfusion ratio Anemic hypoxia Decreased total amount of O bo2nd to hemoglobin Typical causes: blood loss; anemia (low [Hb] or altered HbO bi2ding); carbon monoxide poisoning Ischemic hypoxia Reduced blood flow Typical causes: heart failure (
More Less

Related notes for BMS 420

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.