LIFE 210 Lecture Notes - Enthalpy, Thermodynamics, Organelle

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29 Mar 2014
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Gibbs free energy (g) of molecules available for work. G depends on temperature (t), concentration, oxidation state. Change of g ( g), each reaction has a g. H enthalpy; potential and kinetic energy (e) 1st e (h) is conserved in the universe. Erwin schr dinger, in what is life (1944), wondered how can the events in time and space which take place within the spatial boundary of a living organism be accounted for by physics and chemistry? . Nutrients + cell 2 cells + waste. Change in free energy ( g) in cellular reactions. Requires e input or spontaneous in reverse g > 0. Determined by thermodynamics, the change in free energy or g. Described mathematically by g = h t s (t = temperature in k) Entropy ( s) disorder (degrees of freedom, possibilities, probability) G also determined by the concentration of reactants and products. Effect of the actual conditions (for example in the cell)

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