ANSC 2120 Lecture Notes - Lecture 19: Growth Hormone Treatment, Oxidative Deamination, Mammary Gland
Document Summary
Dietary and rumen microbial protein is absorbed, transported in the bloodstream, and metabolized mostly as free amino acids;, some small peptides are also absorbed and metabolized. Major metabolic fates of absorbed amino acids are: protein synthesis, transamination (conversion to other amino acids, catabolism (deamination, oxidation) All tissues are engages in ongoing, semi-continuous protein synthesis by the rate varies greatly among tissues (%/day: liver 21-23, gut 39-45, muscle 2-4. Within a given tissue, rate of protein synthesis is regulates by hormones and the supply of amino acids and energy (atp) Protein synthesis is energetically expensive (synthesis of one peptide bond costs ~5 atp) and accounts for 15-20% of total body energy expenditure: protein synthesis versus degradation. Tissue protein continuously breaks down by the process of proteolysis and therefore requires continuous re-synthesis. Simultaneous occurrence of protein synthesis and degradation allows for fine control of protein deposition: other possible reasons for evolution of protein turnover are: