ANSC 2120 Lecture Notes - Lecture 24: Pyruvate Dehydrogenase, Acetyl-Coa, Essential Amino Acid

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General features: present in all plant and animal cells, widely distributed in (cid:1) (cid:1) feeds (except b12) Example: oxidative decarboxylation of pyruvate to form acetyl coa; this is an energy reaction pyruvate + coa + nad+ acetyl coa + co2 + nadh. Involvement of the b vitamins in this reaction is very important and has four steps : pantothenic acid is an essential component of coenzyme. A (coa: nicotinamide (niacin) is required for the synthesis of. She calls it the rockstar (cid:1) (cid:1) (cid:1) (cid:1: chemical nature. Vitamin b12 contains the trace element cobalt as an essential component of its structure: cobalt: 0. 02 - 0. 1 mg/kg, sources. Microbial synthesis is the only significant source. Widely distributed in animal tissues: esp. high in liver. Plants contain little or none, except through microbial contamination: this made is hard for vegetarians/vegans until it was better understood, functions. Essential coenzyme for methylation reactions: e. g. bacterial synthesis of methionine, transfers of methyl groups.

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