ANSC 2120 Lecture Notes - Lecture 30: Brown Adipose Tissue, Thermogenesis, Adipocyte
Document Summary
Lecture 30: neonatal animal (cid:1) (cid:1) (cid:1) (cid:1) Newborn of precocial species (farm animals and many wild animals) must quickly adapt to relatively cold environments immediately after birth. Lower critical temperature of newborn animals are relatively high because of small body size, sparse hair/wool coat, low tissue insulation. Brown adipose cells contain many fat droplets. Abundant, densely-packed mitochondria adjacent to fat droplets. When stimulated by cold, bat rapidly mobilizes and oxidizes its own fatty acids in the mitochondria. Oxidation process is uncoupled from atp synthesis and therefore produces additional heat. This is esp. important in newborn pigs which have very little fat reserves and do not develop capacity for hepatic gluconeogenesis for several days. Lipids: blood nefa levels are very low at birth, but rapidly increase due to mobilization of body fat reserves. Lecture 30: neonatal animal: digestion of milk fat becomes major source of fatty acids for energy in most tissues and fat deposition in adipose tissue.