BIOMI 2900 Lecture Notes - Lecture 1: Louis Pasteur, Robert Hooke, Germ Theory Of Disease

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Robert hooke = irst to discover microbes. Microbial diversity is massive (cid:2) (cid:2) (cid:2) (cid:2) Louis pasteur = disproved spontaneous generation of life: chemist did experiments with good/bad beer, advanced germ theory of sickness and pasteurization. Robert koch = proved germ theory of disease: 4 postulates. 1/2observe and isolate microbe supposedly causing disease. Introduce microbe to healthy host and same disease is caused. Re-isolate original microbe from the newly diseased host: developed technique for making pure cultures. Watson, crick, franklin = structure of dna. Zuckerland and pauling = molecular sequences record evolution. Woese = universal tree of life based on ribosomal dna: ribosomal rna sequences discovered archaea, over 70 kingdoms (phyla) of bacteria.

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