BIOMI 2900 Lecture Notes - Lecture 6: Dna Replication, Gammaproteobacteria, Phosphodiester Bond

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High fidelity cope of the cellular cookbook is made (to give to (cid:2) (cid:2) offspring cells) Conversion from the language of nucleic acids to amino acids (cid:2) (cid:2) (cid:2) (cid:2) alternating deoxyribose (2" [2 prime] carbon) and phosphate. Nitrogenous bases: c, t, a, and g attached to backbone of. Note connection of phosphate to 3" carbon on deoxyribose and 5" carbons on adjacent deoxyribose. In a double helix, the number of c"s is equal to the number of. Na synthesis by polymerases always happens in 5" to 3" direction. To copy a sequence of nucleotides in dna the double helix must be opened. It takes more energy to malt gc bonds versus at bonds: microbes in extreme environments tend to have more. Melting/ denaturation transforms double stranded dna into two complementary strands. Melt with either temperature or denaturing agents like base. Two complementary, anti parallel strands make up the double.

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