NS 1150 Lecture Notes - Lecture 9: Lipoprotein Lipase, Pancreatic Islets, Fatty Acid Metabolism

• School: Cornell University
• Department: Nutritional Science
• Course: NS 1150
• Professor: David Levitsky

Document Summary

Carbs in the liver: liver decides fate of glucose. Dump into blood: bloodstream into pancreas (rich blood supply) Releases insulin in response to glucose concentration: insulin. Released into blood supply by beta cells when blood glucose rises above. Role of insulin in muscle tissue: insulin attaches to insulin receptors, transports glucose into cell. Also amino acids and fatty acids: also stimulates the synthesis of glycogen used as energy. 100 g in liver: stimulates the synthesis of fat from glucose, sensitivity of muscle insulin receptors is dependent upon movement. Daily exercise more sensitive to storage of glucose: exercise also increases glucose uptake through non-insulin mechanisms. Role of insulin on adipose cells: adipose cells have fat droplets, insulin attaches to insulin receptors, transport glucose and fatty acids into cell when activated, stimulates the synthesis of fat from glucose, simulates lipoprotein lipase. Inside fat cell, when stimulated takes fat outside cell.