ACCT 210 Lecture Notes - Lecture 35: Splenomegaly, Interleukin 10, Cd28
12 Jul 2020
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Nts: read over the learning outcomes for his lecture, they help. Also not sure about the second to last one, have looked up papers but they"re not too helpful. Innate immune cells produce different signal 3 cytokines as they recognise different signals in response to different classes of pathogen (il-12, il-4?). Signal 3 directs differentiation of the most appropriate cd4 t cell subset. Different cd4 t cell subsets enact different downstream effector immune responses. Th17 cells are named as such because they secrete mass amounts of il-17 where as th1 and. Th2 cells are named after the different type of immune responses they induce rather than their cytokines. The role of th17 cells is to initiate immune responses against pathogens that cannot be cleared by th1 or th2. Th1 cells are good at fighting off intracellular bacteria and protozoa, Th2 with parasitic worm and th17 to extracellular bacteria and fungi.
