ACCT 210 Lecture Notes - Lecture 21: Toxoplasmosis, Trematoda, Pathogenic Bacteria

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Describe the basic characteristics of prokaryotes, viruses, prions, protozoa and helminths. Three major forms of life: prokaryotes, bacteria (eubacteria, archaea (archaebacteria, eukaryotes. Prokaryotes: organisms whose cells lack a nucleus and other organelles. Divided into two distinct groups; bacteria and archaea. Pathogenic bacteria = major cause of human disease. Archaea = not major cause of human disease. Prokaryotic cells are much smaller and simpler than eukaryotic cells. Viruses: small infectious agents that can only replicate inside other living cells. They do not possess their own machinery for genome replications, transcription or translation. Prions: infectious agents that are abnormally folded proteins that are replicated in the host by inducing normal proteins of the same type to adopt abnormal structure. Replicates itself without the need of genetic information. Scrapie (sheep), bovine spongiform encephalopathy (bse), creutzfeldt jacob disease (cjd), kuru. Build up (aggregates) of misfolded proteins forms an amyloid plaque that can cause cell death. Consumption of prion aggregates can spread prion diseases.

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